Philly Wellness Center

How Breathing & Physical Health Interact

Key Takeaways

Humans have widely leveraged the connection between breathing and physical health throughout millennia as a healing tool for the disorders of our body and the soul. Our previous article, “Breathing & Psychological Stress: A two-way street,” described the physiological processes that connect the brain and breathing, enabling us to control stress levels and emotions by deliberately changing our breathing. However, a set of similar functions can also heavily influence other core physiological processes that can impact our physical health.

The scientific community’s renewed interest in the mechanics and biology of breathing has shed light on the fundamental mechanisms connecting respiration and the mind and those connecting respiration and physical health. By analyzing them, we can begin to understand how chronic inflammation and over-excitation of our immune system lead to auto-immune disorders, lower back pain, digestion disorders, and more.

As a first step, let’s understand the fundamental biomarkers that characterize how healthy our breathing process is. These include:

These biomarkers reflect our breathing health because they constitute the basic mechanisms by which breathing affects nearly every process in our body, including our digestion, immune response, mitochondrial function, cardiovascular health, and hormonal balance. To understand how all these systems are affected by our breathing, let’s examine, step by step, the sequence of events occurring when the three fundamental breathing variables are perturbed from their average values.

How breathing affects the nervous system?

Breathing and the autonomic nervous system (ANS) are inextricably linked through various mechanisms. ANS is divided into two parts, the Sympathetic Nervous System (SNS) and the Parasympathetic Nervous System (PNS). SNS causes us to go into “fight-or-flight” mode by engaging all the mechanisms required for movement, preservation, and fast reaction. PNS, on the other hand, causes feelings of relaxation and enables us to recover, digest, and heal. The link between ANS and breathing is made possible through how the neurons connect to the different lung parts. Specifically, SNS is connected to the upper part, whereas PNS is connected to the lower lungs. Due to the anatomy of the connection among lungs, SNS, and PNS, when we breathe faster and shallower, we engage SNS and partially deactivate PNS. On the contrary, when we deliberately breathe deeper and slower, we can activate PNS thanks to its connection to the lower part of our lungs and thus enable feelings of relaxation

Breathing continuously faster and shallower, a condition called Chronic Hyperventilation Syndrome (CHS), causes a chronic hyper-activation of SNS setting our body in a perpetual state of increased stress. Engagement of SNS signals to our body the presence of danger and thus triggers a chain of reactions aimed to prime us for facing it. Although these processes have been developed over thousands of years of evolution and can be life-saving given their effect of setting us ready to respond to threats, their constant activation causes a cascade of negative repercussions. Here are the main mechanisms and physiological systems affected:

– Immune system hyperactivation: Our central nervous system is also interconnected with our immune system through a molecule called Cytokines. Cytokines are a general category of small proteins that play an essential role in cell signaling. They control the growth and activity of immune blood cells enabling them to trigger inflammation and respond to pathogens. Overactivation of the sympathetic nervous system can therefore result in constant activation of the immune system, leading to chronic inflammation and auto-immune disorders.

How the mechanics of breathing affect our body?

In addition to the nervous-based interaction between breathing and several key sectors of our physiology, breathing also affects our health through the mechanics of respiration.

– Cardiovascular Strain: One of the most critical systems in our breathing apparatus is the diaphragm, a dome-shaped muscle that sits between the lungs and the abdominal area. The diaphragm moves down and up, and we inhale and exhale. Our abdomen contains 25-30% of our body’s total blood volume making it one of the most blood-dense areas of our body. Rapid and shallow breathing reduces the engagement of the diaphragm and can, over time, lead to diaphragmatic atrophy, the state where the diaphragm weakens and moves less during respiration. The movement of the diaphragm aids in abdominal blood circulation, which represents a significant part of the overall blood circulation in our body. This is why the diaphragm is also referred to as the second heart. As a result, diaphragmatic atrophy leads to a minor contribution of the diaphragm on blood circulation and thus increases the load our heart has to support whole-body circulation.

– Posture and skeletal muscular disorders: As described above, the diaphragm is a critical component of our breathing apparatus. Strong diaphragmatic engagement increases abdominal pressure, engages the abdominal muscles, and thus provides support to our core and lower back. On the contrary, weak diaphragmatic movement caused by shallow breathing weakens our core stability and is, therefore, a key factor for developing lower back pain and other skeletal muscle disorders.

– Brain oxygenation: Breathing and hyperventilation is the primary regulator of the balance between oxygen and carbon dioxide in our blood. As breathing becomes faster, the amount of air exhaled increases along with the amount of carbon dioxide (CO2) expelled through the body. As more CO2 leaves the body, CO2 circulating in the blood declines, causing a cascade of adverse effects as it is responsible for two critical biological functions. First, CO2 enables oxygen molecules to detach from hemoglobin (the substance in our blood responsible for transporting oxygen from our lungs across the body) and enter the cells that need them to produce energy. Second, CO2 regulates how narrow or wide our arteries are and the amount of blood delivered across the body. As a result, a reduction of CO2 levels in the blood will cause a tighter connection between oxygen molecules and hemoglobin, making it harder for oxygen to enter cells and narrowing the arteries, diminishing blood delivery to the brain and across the body.

The following graph provides a summary of how these mechanisms interact with each other:


Breathing is a crucial regulator of several critical functions, including blood chemistry, nervous system balance, and abdominal pressure. Learning how to breathe in accordance with your metabolic need can become a healing factor for many psychosomatic disorders and prevent the onset of chronic conditions. As a result, breathing is the most influential physiological function that’s in your control.

Call us at Philly Wellness Center to start your journey.

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